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Kidneys, electrolytes and minerals

Creatinine blood test: what a high or low result means

What a creatinine blood test measures, what high or low creatinine can mean, and what to ask your doctor.

Also written as:serum creatinineCrcreat
Written and reviewed by Nick Lamb, PhD, medical writer Patiently AI is an MHRA-registered Class I medical device Last reviewed 28 October 2026

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What is creatinine?

Creatinine is a waste product made by your muscles as they work. Your kidneys filter it out of your blood and into your urine, so the level in your blood is a useful guide to how well your kidneys are working. Creatinine is part of a kidney blood test called U&E (urea and electrolytes), or a metabolic panel in the US, and it is used to calculate your eGFR.

Why is this test done?

What does a high creatinine mean?

A high creatinine can mean your kidneys are filtering less well, either for a short time or over the long term.

Possible reasons include:

What does a low creatinine mean?

A low creatinine is rarely a problem. It usually reflects lower muscle mass.

Possible reasons include:

Why we don't list a "normal range". Reference ranges differ between laboratories and can depend on your age, sex and whether you are pregnant. The range printed next to your result on your own report is the one that applies to you, so use that, and talk to your doctor about what your result means for you.

What can affect your creatinine result?

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Questions to ask your doctor

Frequently asked questions

Can drinking more water lower creatinine?

If your creatinine is raised because you were dehydrated, drinking enough fluid can bring it back down. It will not change creatinine that is raised because of kidney disease.

Why does muscle affect creatinine?

Creatinine comes from muscle, so people with more muscle make more of it. That is why a bodybuilder may have a higher result with perfectly healthy kidneys.

Is creatinine the same as creatine?

No, but they are related. Creatine is a substance used by muscles for energy, and creatinine is the waste product it breaks down into. Creatine supplements can raise creatinine.

Can Patiently AI explain my creatinine result?

Yes. Paste your results, or upload a photo, PDF or Word file, and Patiently AI explains them in plain English, sticking to the numbers and ranges on your own report rather than adding its own, and suggests questions to ask your doctor. It is free, needs no account, and removes identifying details on your device first.

Important: This page is general information to help you understand a test result, not medical advice. What a result means depends on your circumstances, symptoms and other results. Patiently AI rewrites medical text to make it easier to read; it may oversimplify or miss nuance and does not provide diagnosis or treatment recommendations. Always discuss your results with your doctor. If you feel very unwell, seek urgent medical help.